Well the first shot wasn't that bad. The needles aren't that big which is good. I had to have Jeremy give me the shot. So we cleaned the area on my stomach and he loaded the pen with the serum and he was like you ready and I was pushing me and he like you can't do that hold onto the doorway. So wham and it was done. It burned a bit but that is to be expected since the pen is kept in the fridge. Plus the nurse that it's like that until it gets into the skin and my system. So I guess its not all that bad.